Recovery and Lifespan of Red Blood Cells From Pathogen-reduced, Stored Blood Units

Subject Inclusion Criteria * Up to 12 subjects will be enrolled for a maximum of 6 eligible subjects in the pilot study to provide preliminary RBC survival data to support a subsequent adequately powered study capable of addressing the two objectives as stated above. * Age ≥18 years, of either gender * Normal health status (as determined by the Investigator review of medical history and blood donor physical exam) * Weight over 140 lbs. * Complete blood count (CBC; including RBC indices MCV, MCH, MCHC, and RDW) and serum chemistry values within normal limits (including calcium, bicarbonate, chloride, inorganic phosphate, potassium, sodium, cholesterol, glucose, total protein, triglycerides, LDH, ALT, AST,total bilirubin, BUN, creatinine). Values outside of normal reference range if considered not to be clinically significant may be allowed with a protocol exception. * Minimum hemoglobin levels of 13 g/dL for female and 14 g/dL for male subjects * Negative blood donor screening test panel for HIV, HBV, HCV, HTLV, Syphilis, WNV and Zika virus * Female subjects of childbearing potential and male subjects must agree to use a medically acceptable method of contraception throughout the study periods. A barrier method of contraception must be included, regardless of other methods. * Meet or exceed AABB guidelines for blood donation (with the exception of travel deferrals). * Signed and dated informed consent form Subject Exclusion Criteria * Clinically significant acute or chronic…