CompletedNot Applicable

The Influence of Glycemic Control and Obesity on Energy Balance and Metabolic Flexibility in Type 1 Diabetes

United States32 participantsStarted 2018-03-08

Plain-language summary

The purpose of this study is to measure the metabolic phenotype of a range of body weights in individuals with and without type 1 diabetes.

Age range19 Years – 30 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

✕. Type 2 diabetes
✕. History or presence of cardiovascular disease (unstable angina, myocardial infarction or coronary revascularization within 6 months, clinically significant abnormalities on EKG, presence of cardiac pacemaker, implanted cardiac defibrillator)
✕. Liver disease (AST or ALT \>2.5 times the upper limit of normal), history of hepatitis
✕. Kidney disease (creatinine \>1.6 mg/dl or estimated glomerular filtration rate (GFR)\<60 ml/min)
✕. Dyslipidemia, including triglycerides \>800 mg/dl, LDL \>200 mg/dl
✕. Anemia (hemoglobin \<12 g/dl in men, \<11 g/dl in women)
✕. Thyroid dysfunction (suppressed thyroid-stimulating hormone (TSH), elevated TSH \<10 µIU/ml if symptomatic or elevated TSH \>10 µIU/ml if asymptomatic)
✕. Uncontrolled hypertension (BP \>160 mmHg systolic or \> 100mmHg diastolic)

Energy Expenditure

Timeframe: 24 hours

NCT IDNCT03379792

SponsorAdventHealth Translational Research Institute

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2020-07-20

Results submitted2022-06-21