Study to Compare Exposure of TA Following Administration of Either FX006 or TAcs in Patients With Bilateral Knee OA

Inclusion Criteria: * Written consent to participate in the study * Male or female greater than or equal to 40 years of age * Symptoms consistent with OA in both knees for greater than or equal to 6 months prior to Screening (patient reported is acceptable) * Currently meets ACR Criteria (clinical and radiological) for OA in both knees * Knee pain in both knees for greater than 15 days over the last month (as reported by the patient) * Body mass index (BMI) less than or equal to 40 kg/m2 * Morning serum cortisol result within normal range at Screening (5-23 mcg/dL or 138-635 nmol/dL) * Ambulatory and in good general health * Willing and able to comply with the study procedures and visit schedules and able to follow verbal and written instructions. * Willing to abstain from use of protocol-restricted medications during the study Exclusion Criteria: * Reactive arthritis, rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, or arthritis associated with inflammatory bowel disease * History of infection in either knee joint * Clinical signs and symptoms of active knee infection or crystal disease in either knee within 1 month of Screening * Unstable joint (such as a torn anterior cruciate ligament) in either knee within 12 months of Screening * Presence of surgical hardware or other foreign body in either knee * Surgery or arthroscopy of either knee within 12 months of Screening * IA treatment of any joint with any of the following agents within six (6) months of …