Narcotic Versus Non-narcotic Medication for Pain Management After Wrist/Hand Fractures (NCT03375593) | Clinical Trial Compass
UnknownPhase 4
Narcotic Versus Non-narcotic Medication for Pain Management After Wrist/Hand Fractures
Canada250 participantsStarted 2019-08-01
Plain-language summary
The purpose of this study is to evaluate two drug options for pain control in patients following wrist injury. Participants will be randomized to one of the 2 pain relief treatments to determine what treatment provides the most effective pain relief
Who can participate
Age range18 Years – 90 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* All patients 18 and older undergoing non-operative management of a hand or wrist fracture will be considered eligible.
* Able to read and speak English
Exclusion Criteria:
* pain exceeding 7/10 on numeric rating scale or 35/50 on PRWE pain scale at enrollment
* nerve injury
* surgeon decision that surgery is required
* history of chronic opioid use
* documented or suspected substance abuse
* individuals currently on daily use of ibuprofen, acetaminophen or other pain-altering medication including medications like Neurontin (gabapentin) and Ultram (tramadol)
* individuals with documented or suspected chronic pain syndrome, reported allergy or adverse reaction to hydrocodone, acetaminophen, or ibuprofen
* history or symptoms of serious medical problem in the last year (i.e., arrhythmia, impaired cardiovascular function, gastrointestinal bleeding, liver disease, renal disease)
* patients with active peptic ulcer disease (history of severe heartburn)
* symptoms of infection
* pregnant or lactating women
* diagnosis of cognitive impairment
* unable to provide informed consent
* unable or unwilling to fill out the forms
* prior fracture in same hand
* on Coumadin or Plavix
* other medical or psychological health conditions that preclude them from receiving either intervention
* or unable to return for follow-up visits
What they're measuring
1
Pain
Timeframe: 0-2 weeks
Trial details
NCT IDNCT03375593
SponsorLondon Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's