WithdrawnPhase 2

Liraglutide on Decreasing Parenteral Support in Short Bowel Patients (SLIPS)

Stopped: No participants recruited. Not able to recruit due to COVID 19.

United Kingdom0Started 2017-10-20

Plain-language summary

Pilot study looking at the effect on Liraglutide in the reduction of parenteral support in patients with short bowel.

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

✓. Short bowel (≤200cm) as a result of major intestinal resection (e.g. due to injury, volvulus, vascular disease, Crohn's disease).
✓. Jejunostomy patients only
✓. 12 continuous months of parenteral support (PS) dependency prior to enrolment.
✓. PS required at least 3 times per week to meet their caloric, fluid or electrolyte needs due to on-going malabsorption.
✓. Stable PS for at least 4 consecutive weeks immediately prior to first dose of liraglutide. Stability is described as:
✓. Actual PS usage should match prescribed PS;
✓. Baseline 48-hour urine output is 1-2 L/24 hours.
✓. Body mass index ≥ 19.5 kg/m2.

Improvement in parenteral support

Timeframe: 20 weeks post start of drug

NCT IDNCT03371862

SponsorImperial College London

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2020-08-06