CompletedNot Applicable

Prevention of Adolescent Risky Behaviors: Neural Markers of Intervention Effects

United States146 participantsStarted 2017-12-11

Plain-language summary

Adolescence is a time of biological and behavioral changes that can lead to risky and dangerous behaviors, and African-American youth are highly vulnerable to the consequences of risky behavior, including HIV/AIDS and violence, leading to premature death. The investigators previously showed that an intervention program reduces HIV-risk vulnerability behaviors in many African-American youth. The investigators aim to measure how the program affects different regions of the brain in order to better prevent or reduce such risky behaviors among African-American youth.

Who can participate

Age range11 Years – 14 Years

SexALL

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Inclusion Criteria: * Subject is of African-American racial status (self-reported) * Subject can speak and read English * Subject and parent/legal guardian agree to participate in the 6-week PAAS program * Subject and parent/legal guardian agree to complete all assessments * Subject must meet MRI safety eligibility Exclusion Criteria: * Subject has a major medical problem (e.g. neurological disorders) * Subject is on medication(s) that affects the central nervous system * Subject has behavioral/emotional problems at a clinical level (parent and/or youth report) * Subject is pregnant or suspected of being pregnant (based on pregnancy test) * Subject is color-blind * Subject has claustrophobia * Subject has metallic implants * Subject drinks alcohol in the week prior to entry into the study (based on urine drug screen) * Subject uses drugs in the week prior to entry into the study (based on urine drug screen)

What they're measuring

Changes in Emotional Regulation

Timeframe: 18 weeks (from pre-intervention to 3-months after post-intervention)

Trial details

NCT IDNCT03370393

SponsorUniversity of California, Irvine

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-03-31

Results submitted2025-07-20