A Proof-of-Concept Study of Danicopan for 6 Months of Treatment in Participants With C3 Glomerulopathy (C3G)

Key Inclusion Criteria: * Had biopsy-confirmed primary C3G * Had clinical evidence of ongoing disease based on significant proteinuria, attributable to C3G disease in the opinion of the Principal Investigator (PI), and present prior to study entry and confirmed during Screening * Was willing to comply with vaccination requirements. Key Exclusion Criteria: * Had a history or presence of any clinically relevant co-morbidities that would make the participant inappropriate for the study * Had ever received danicopan * Had more than 50% fibrosis or more than 50% of glomeruli with cellular crescents on the pre-treatment renal biopsy * Had an estimated glomerular filtration rate \<30 milliliters/minute/1.73 meters squared at the time of screening or at any time over the preceding 4 weeks * Was a renal transplant recipient or receiving renal replacement therapy * Had a history of a major organ transplant or hematopoietic stem cell/marrow transplant * Had evidence of monoclonal gammopathy of unclear significance, infections, malignancy, autoimmune diseases, or other conditions to which C3G is secondary * Had other renal diseases that would interfere with interpretation of the study * Had been diagnosed with or showed evidence of hepatobiliary cholestasis * Females who were pregnant, nursing, or planning to become pregnant during the study or within 90 days of study drug administration * Had a history of febrile illness, a body temperature \>38°Celsius, or other evidence of a clinic…