Bilateral Orthotopic Lung Transplant - Bone Marrow Transplant

Inclusion Criteria: * Subject and/or parent guardian must be able to understand and provide informed consent; * Subject fulfills criteria for United Network of Organ Sharing (UNOS) listing; * Subject must have evidence of an underlying primary immunodeficiency for which Bone Marrow Transplant (BMT) is clinically indicated. Examples of such diseases include, but are not limited to: * Severe Combined Immunodeficiency (SCID) * Combined immunodeficiency with defects in T-cell-mediated immunity, including Omenn syndrome and DiGeorge Syndrome * Severe Chronic Neutropenia * Chronic Granulomatous Disease (CGD) * Hyper Immunoglobulin E (IgE) Syndrome or Job's Syndrome * CD40 or CD40L deficiency * Wiskott-Aldrich Syndrome * Mendelian Susceptibility to Mycobacterial Disease * GATA2-associated Immunodeficiency. * Subjects must have evidence of end-stage lung disease and be candidates for bilateral orthotopic lung transplant as determined by the lung transplant team; * Glomerular filtration rate (GFR) ≥ 50 mL/min/1.73 m\^2; * Aspartate aminotransferase (AST), Alanine aminotransaminase (ALT) ≤ 4x upper limit of normal, total bilirubin ≤ 2.5 mg/dL, normal INR; * Cardiac ejection fraction ≥ 40% or shortening fraction ≥ 26%; * Negative pregnancy test for females \>10 years old or who have reached menarche, unless surgically sterilized; * All females of childbearing potential and sexually active males must agree to use a Food and Drug Administration (FDA) approved method of…