Rapid Pleurodesis Through an Indwelling Pleural Catheter (NCT03325192) | Clinical Trial Compass
TerminatedNot Applicable
Rapid Pleurodesis Through an Indwelling Pleural Catheter
Stopped: Slow enrollment
United States11 participantsStarted 2017-12-12
Plain-language summary
The primary objective of the study is to evaluate whether the use of a rapid pleurodesis protocol using 10% iodopovidone immediately after tunneled pleural catheter placement improves time to IPC removal compared to patients who receive an IPC alone.
Who can participate
Age range18 Years
SexALL
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Inclusion criteria
✓. Diagnosis of MPE as defined by
✓. A diagnosis a pleural effusion in the setting of known malignancy. AND
✓. Confirmed malignant involvement of the pleural space by fluid cytology or pleural biopsy. OR
✓. Evidence of pleural disease on radiographic imaging. OR
✓. A recurrent effusion with no other identifiable cause after thorough workup.
✓. Symptomatic from the pleural effusions (shortness of breath, cough, or chest pain)
✓. Prior thoracentesis with post procedure symptomatic relief
✓. Recurrence of symptoms with re-accumulation of pleural effusion
Exclusion criteria
✕. Malignant pleural effusion due to a hematologic malignancy
✕. ECOG \>4
✕. Any history of trapped lung
✕. Prior attempted pleurodesis on the affected site