Intracranial Collaterals in Acute Stroke and Clinical Outcome (NCT03311386) | Clinical Trial Compass
CompletedNot Applicable
Intracranial Collaterals in Acute Stroke and Clinical Outcome
Egypt40 participantsStarted 2017-11-23
Plain-language summary
Assessment of the evolution of intracranial collaterals and its relationship with functional outcomes in acute ischemic stroke (AIS) patients treated with IV tissue plasminogen activator (tPA).
Who can participate
Age range18 Years – 75 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
IInclusion Criteria:
* Patient presenting to the emergency department with symptoms consistent with ischemic stroke.
* Age \> 18 yrs.
* Evidence of a visible and symptomatic intracranial occlusion on baseline CT-angiography (intracranial ICA, M1 MCA segment +/- intracranial ICA, proximal M2 MCA).
* Treatment with IV tPA.
Exclusion Criteria:
* Intracranial hemorrhage (ICH) identified on baseline CT.
* Previous moderate to large stroke in the ipsilesional hemisphere.
* Modified Rankin Scale \> 2 at baseline.
* Unable to have CT-angio performed due to recent estimated creatinine clearance eCCr\<60 ml/min, contrast allergy or other reasons.
* Any terminal illness (patient not expected to survive \> 1 year).