CompletedNot Applicable

Periodontal Therapy in Thalassemia Major Patients

52 participantsStarted 2016-01-11

Plain-language summary

The study aims to evaluate the effect of local non surgical periodontal therapy on the systemic pro-inflammatory markers in the β-thalassemia (TM-β) patients with chronic periodontitis and systemically healthy demographically matched controls with chronic periodontitis. Both groups will receive non surgical periodontal therapy.

Who can participate

Age range10 Years – 18 Years

SexALL

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Inclusion criteria

✓. Written and verbal consent
✓. (TM-β) patients with gingivitis
✓. Age: ≥10 years
✓. Patients who have received or are receiving iron chelation therapy with deferasirox, calcium, vitamin D, and regular erythrocyte transfusion.

Exclusion criteria

✕. Presence of hepatitis B or C or HIV-AIDS (Human immunodeficiency Virus- Acquired immunodeficiency syndrome).
✕. Presence of any other known systemic disease.
✕. Use of antibiotics or anti-inflammatory drugs within the past 6 months.
✕. Dental prophylaxes in the last 6 months

What they're measuring

Systemic pro-inflammatory cytokines

Timeframe: 6 weeks

Trial details

NCT IDNCT03311243

SponsorKing Saud University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2017-04-10

View on ClinicalTrials.gov More Thalassemia Major trials