Thiamine Supplementation in High Risk Cardiac Surgery Patients (NCT03306732) | Clinical Trial Compass
CompletedPhase 4
Thiamine Supplementation in High Risk Cardiac Surgery Patients
Russia40 participantsStarted 2017-10-19
Plain-language summary
This pilot trial will evaluate the ability of thiamine to affect on postoperative vasoplegia in high risk cardiac surgery patients
Who can participate
Age range18 Years
SexALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Valve surgery + CABG that required cardiac surgery with CPB
* Aged 18 years or older
* Signed informed consent
Exclusion Criteria:
* Emergency surgery
* Chronic kidney disease of G4-G5 categories according to KDIGO criteria (at least one of the following present for \> 3 months: glomerular filtration rate ≤ 29 ml/min/1.73 m2, history of kidney transplantation)
* Known allergy to thiamine
* Pregnancy
* Current enrollment into another RCT (in the last 30 days)
* Previous enrollment and randomisation into the APPLY trial
* Administration of thiamine in the previous 30 day
What they're measuring
1
Recruitment rate
Timeframe: 8 month
2
Compliance with the protocol
Timeframe: 8 month
Trial details
NCT IDNCT03306732
SponsorMeshalkin Research Institute of Pathology of Circulation