CompletedNot Applicable

Short-Term Endogenous Hydrogen Sulfide Upregulation

United States9 participantsStarted 2017-09-14

Plain-language summary

This research study will compare the impact of dietary restriction pre-operatively before carotid endarterectomy compared to the standard nutrition that a patient typically eats. The investigators want to find out how patients comply and generally how well patients do with this type of dietary restriction before their surgery since animal studies suggest that short - term dietary restriction may be beneficial before surgery.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * consenting adults (men and women) * clinical indication for carotid endarterectomy (CEA) as determined by attending vascular surgeon * if symptomatic, patients must be able to safely have surgery timed for PCR intervention Exclusion Criteria: * intolerance or allergy to any ingredients in the PCR diet (ScandiShake ingredients or almond milk/nuts) * active infection * pregnancy * malnutrition determined by serum albumin lower than BWH reference value of 3.5 g/dL * active drug dependency or alcoholism that could interfere with protocol adherence * active non-cutaneous cancer under treatment with chemotherapeutic

What they're measuring

subject compliance with PCR

Timeframe: three days pre-operatively

Trial details

NCT IDNCT03303534

SponsorBrigham and Women's Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2018-06-01

View on ClinicalTrials.gov More Carotid Stenosis trials