A Study of the Abuse Potential of Lasmiditan in Participants Who Are Recreational Drug Users

Inclusion Criteria: * Are overtly healthy males or females, as determined by medical history and physical examination. * Have a body mass index (BMI) of 18 to 32 kilograms per meter squared (kg/m²) inclusive, at the time of screening. * Must be recreational drug user and agree not to consume any recreational drugs during the study. Exclusion Criteria: * Have known allergies to lasmiditan, alprazolam, related compounds, or any components of the formulation, or a history of significant atopy. * Are currently seeking or participating in treatment for addiction or substance-related disorders, or have recovered from substance abuse disorder. * Are currently taking excluded prescription or over-the-counter (OTC) medications. * Have a history of significant sleep disorder, including sleep apnea or narcolepsy. * Have a history of orthostatic hypotension, vertigo, syncope, or presyncope. * Have a history of brain injury, including a history of concussions.