Encapsulated Nutrients' Acute Effects on Appetite; ENcapSulated, nUtRiEnts (ENSURE)
Denmark34 participantsStarted 2017-11-13
Plain-language summary
A double-blind, randomized crossover design with four arms including three experimental conditions and placebo will be applied. After having successfully completed screening procedures, eligible participants will be invited to four separate test days. The test days cannot be within the same week, however there is no upper limit for days in between, as long as the participants remain weight stable and do not change diet or physical activity level. Significant changes in diet, physical activity level (evaluated by the sub-investigator) or weight change ±3 kg over the course of the study (from screening to completion of the last test day) results in exclusion of that subject.
Who can participate
Age range18 Years – 60 Years
SexMALE
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Inclusion Criteria:
* Participants who have provided written informed consent
* Healthy men
* Age between 18 and 60 years
* BMI between 18.5-32 kg/m2
* Regular breakfast eaters (eating breakfast ≥ 4 times a week)
Exclusion Criteria:
* Participants unable to consume or known to get nausea from consuming 20 medium sized capsules (placebo capsules will be provided at screening for test of ability to consume the relevant amount of capsules)
* Participants not able to comply with the study protocol, including consumption of the specific study foods (pictures of study foods shown at screening)
* Any known food allergies or food intolerance likely to affect the present study
* Significant health problems as judged by the principal investigator
* Taking any medication or supplements known to affect appetite or body weight within the past month and/or during the study as judged by the study professional
* Intake of probiotic supplements (any kind of supplements but not including foods containing probiotic) \< 4 weeks before study start
* Intake of probiotic supplements (any kind of supplements but not including foods containing probiotic) during the study
* Use of systemic medical treatment likely to interfere with evaluation of the study parameters as judged by the principal investigator
* Smoking, smoking cessation within the past 3 months or nicotine use (electronic cigarettes, gum etc.). Irregular smokers accepted
* Self-reporting currently dieting or having lost/gained signifi…