CompletedNot Applicable

Assessing Fluid Responsiveness With PWTT

Germany38 participantsStarted 2016-05-31

Plain-language summary

Pulse wave Transit time (PWTT) is a parameter calculated from ECG and pulseoximeter. It is supposed to help assessing the preload Status and guide intraoperative fluid therapy. This Project aims to validate the benefit of PWTT assessment in an observational clinical fluid study. In case of hypovolemia, patients will receive a fluid Bolus and hemodynamic data from clinical Standard Monitoring, esophageal doppler and PWTT will be recorded before and after the fluid Bolus. Receiver operating characteristic (ROC) curve will be used to determine the validity of PWTT as indicator for fluid responsiveness and its cut off value.

Who can participate

Age range18 Years – 80 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Adults 18 - 80 years old * elective open abdominal surgery * clinical indication for direct arterial blood pressure Monitoring * supine Position intraoperatively Exclusion Criteria: * under 18 years, over 80 years old * pregnant * no informed consent * systemic inflammatory response syndrome (SIRS) or Sepsis * Severe cardiac, coronary or vascular disease * Arrythmia * Cardiac valves anomaly * BMI \> 35 * American Society of Anesthesiologists (ASA) physical status classification system: 4 * Lung disease that excludes Ventilation with a tidal volume \>8ml/kg * esophageal pathology * planned prone position surgery

What they're measuring

PWTT change before and after fluid bolus

Timeframe: 1 day

Trial details

NCT IDNCT03280953

SponsorJohannes Gutenberg University Mainz

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2018-12-31

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