Safety and Immunogenicity of Concomitant Administration of EV71 Vaccine With EPI Vaccines

Exclusion criteria

• ✕. Any serious adverse event that has a causal relationship with the investigated vaccine (except the group II)
• ✕. Severe allergic reactions or hypersensitivity after vaccination (including urticaria / rash appear within 30 minutes after vaccination, except the group II )
• ✕. Any confirmed or suspected autoimmune disease or immunodeficiency disease (e.g., HIV infection)
• ✕. New chronic diseases or acute stage of chronic diseases
• ✕. Other reactions (including severe pain, severe swelling, severe activity limitation, persistent hyperthermia, severe headache or other systemic or local reactions) determined by the investigators
• ✕. Acute diseases (moderate or severe diseases with or without fever)
• ✕. Axillary temperature\> 37.0 ℃