Use of Adipose Derived Regenerative Cells in Bilateral Femoral Head Osteonecrosis

Inclusion Criteria * Males and females 22-70 years of age. * No articular surface collapse of the femoral heads as measured by MRI. * Target disease or condition: Bilateral pre-collapse osteonecrosis of the femoral head. * Atraumatic osteonecrosis of the femoral head (all other etiologies eligible including corticosteroid and alcohol induced osteonecrosis). * Ability to safely undergo liposuction that will result in the harvest of a sufficient quantity of adipose tissue (approximately 360 mL). A plastic surgeon evaluation will be performed in order to determine adequate adipose tissue is available for harvest. * Capacity to provide informed consent * Ability to comply with protocol * Normal laboratory values of CBC, CRP, AST, ALT, Bilirubin (total \& direct), BUN and Creatinine. Exclusion Criteria: * Post traumatic femoral head osteonecrosis. * Osteonecrosis of the femoral head in stages ≥ IIIA according to the Steinberg classification. * Asymptomatic osteonecrosis on exam * Flattening of the femoral head (Steinberg classification Type IV) or articular cartilage collapse at the time of core decompression surgery. * Septic arthritis, stress fracture, or non-osteonecrosis metabolic bone diseases (e.g., Paget's disease of bone, osteogenesis imperfecta, primary hyperparathyroidism, osteopetrosis, and fibrous dysplasia including monostotic, polyostotic, and McCune-Albright syndrome). * Skeletal immaturity. * Known history of HIV, or has active Hepatitis B or active Hepatitis C.…