Open Label Safety Study in Acute Treatment of Migraine

Key Inclusion Criteria: * Subjects with 2-8 moderate to severe migraines/month * Age of onset of migraines prior to 50 years of age * Migraine attacks, on average, lasting 4-72 hours if untreated * Ability to distinguish migraine attacks from tension/cluster headaches * Patients with contraindications for use of triptans may be included provided they meet all other study entry criteria Key Exclusion Criteria: * History of basilar migraine or hemiplegic migraine * History of HIV disease * History with current evidence of uncontrolled, unstable or recently diagnosed cardiovascular disease, such as ischemic heart disease, coronary artery vasospasm, and cerebral ischemia. * Uncontrolled hypertension or uncontrolled diabetes (however, patients can be included who have stable hypertension and /or diabetes for 3 months prior to screening * History of gastric or small intestinal surgery or has a disease that causes malabsorption * BMI ≥ 30 * HbA1c ≥ 6.5%