Comparison of EVD Catheter Diameter on Occlusion and Replacement (NCT03248739) | Clinical Trial Compass
TerminatedNot Applicable
Comparison of EVD Catheter Diameter on Occlusion and Replacement
Stopped: Preliminary data did not show a difference. PI decided to terminate study.
United States33 participantsStarted 2017-06-12
Plain-language summary
A randomized trial comparing small versus large catheters in terms of occlusion and need for replacement to confirm differential occlusion risk based on catheter size. This study will be done to determine whether external ventricular drain catheter diameter has any effect on risk of occlusion.
Who can participate
Age range18 Years – 85 Years
SexALL
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Inclusion Criteria:
* Adult patients (18-85 years old) with a Glasgow Coma Scale (GCS) score of 7 or higher requiring frontal EVD placement.
* Diagnoses: spontaneous subarachnoid hemorrhage, intraventricular hemorrhage, intraparenchymal or cerebellar hemorrhage due to aneurysm, arteriovenous malformation, arteriovenous fistula, hypertension, or idiopathic etiology.
* Also included are patients for whom the attending neurosurgeon decides that frontal EVD placement is indicated for patient treatment with planned cerebrospinal fluid (CSF) drainage for 72 hours or more.
Exclusion Criteria:
* GCS of 6 or less
* Hunt and Hess subarachnoid hemorrhage grade of 5.
* Age 86 or greater, or age 17 or less.
* Patient cannot consent and next of kin cannot consent prior to procedure.
* Diagnosis of traumatic brain injury, as the EVD is often clamped for extended periods of time.
* Patients anticoagulated prior to admission with warfarin, Effient, Plavix, therapeutic heparin infusion, therapeutic subcutaneous lovenox, therapeutic subcutaneous arixtra, or other therapeutic anticoagulant or antiplatelet agent (ASA not included).
* Plan for EVD placement through non-frontal burr hole.
What they're measuring
1
Number of Participants With Permanent Catheter Occlusions