Evaluation of The Safety And Performance of The Freedom Total Knee® System With The PEEK-OPTIMA Femoral Component

INCLUSION CRITERIA: * Male and female subjects aged 50 years of age or older and less than 75 years of age (\>50 and \<75 years). * Subjects who require a uni-lateral knee prosthesis and have been evaluated as appropriate candidates for a total knee arthroplasty by the Investigator. * Subjects with a primary diagnosis of end-stage symptomatic primary knee osteoarthritis * Subjects who, in the opinion of the Investigator, are able to understand this clinical investigation, co-operate with the investigational procedures and are willing to return to the hospital for all the required post-operative follow-ups. * Subjects who are able to give voluntary, written informed consent to participate in this clinical investigation and from whom consent has been obtained. EXCLUSION CRITERIA: * Subjects who, in the opinion of the Investigator, have an existing condition that would compromise their participation and follow-up in this clinical investigation. * Subjects who are known drug or alcohol abusers or with psychological disorders that could affect follow-up care or treatment outcomes. * Subjects who have participated in a clinical study with an investigational product in the last 6 months. * Subjects with other significant disabling problems from the muscular-skeletal system other than in the knees (i.e muscular dystrophy, polio, neuropathic joints). * Subjects with a BMI of 32 or above. * Subjects with a current or active history of malignancy, active or suspected infection, Paget…