CompletedNot Applicable

Corneal Autograft for Limbal Dermoid

China19 participantsStarted 2022-05-10

Plain-language summary

To investigate the clinical efficacy of femtosecond laser-assisted autologous lamellar keratoplasty in treating corneal dermoids.

Age range5 Years – 35 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

✓. Age between 5 to 35 years old,
✓. Patients with limbal dermoid, scheduled for elective surgical excision,
✓. The distance of less than 5 mm of lesion encroachment into the cornea,
✓. The participant or their legal guardian has voluntarily chosen to participate in this study, has signed the informed consent form, and has demonstrated a high level of adherence to the study protocols and cooperation throughout the follow-up process.

✕. Keratoconus,
✕. High myopia with a spherical equivalent of -15.0 D or less,
✕. Ocular and facial active inflammation such as keratitis, trachoma, dacryocystitis, blepharitis, meibomian gland dysfunction, Sjogren's syndrome, cicatricial pemphigoid etc,
✕. Corneal or ocular surface infection within 30 days prior to study entry,
✕. Severe cicatricial eye disease,
✕. Ocular surface malignancy,
✕. Ocular comorbidities that affect the prognosis of transplantation, such as advanced glaucoma or retinal diseases,
✕. History of allo-limbal transplantation, penetrating keratoplasty or anti-glaucoma filtering surgeries,

Corneal Thickness

Timeframe: 1 week, 1 month, 3 months, 6 months, 9 months, 12 months and 18 months postoperatively

Corneal Transparency

Timeframe: Preoperatively, 1 week, 1 month, 3 months, 6 months, 9 months, 12 months and 18 months postoperatively

NCT IDNCT03217461

SponsorChunxiao Wang

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-11-29

Who can participate

Age range5 Years – 35 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

✓. Age between 5 to 35 years old,
✓. Patients with limbal dermoid, scheduled for elective surgical excision,
✓. The distance of less than 5 mm of lesion encroachment into the cornea,
✓. The participant or their legal guardian has voluntarily chosen to participate in this study, has signed the informed consent form, and has demonstrated a high level of adherence to the study protocols and cooperation throughout the follow-up process.

✕. Keratoconus,
✕. High myopia with a spherical equivalent of -15.0 D or less,
✕. Ocular and facial active inflammation such as keratitis, trachoma, dacryocystitis, blepharitis, meibomian gland dysfunction, Sjogren's syndrome, cicatricial pemphigoid etc,
✕. Corneal or ocular surface infection within 30 days prior to study entry,
✕. Severe cicatricial eye disease,
✕. Ocular surface malignancy,
✕. Ocular comorbidities that affect the prognosis of transplantation, such as advanced glaucoma or retinal diseases,
✕. History of allo-limbal transplantation, penetrating keratoplasty or anti-glaucoma filtering surgeries,