RE-GENERATION: The Safety and Performance of the Relay Pro and Relay NBS Pro Stent-graft Devices in the European Union (EU)

Inclusion Criteria: * Patient diagnosed with thoracic aorta pathology (aneurysm, pseudoaneurysm, dissection, penetrating ulcer or intramural hematoma) suitable for TEVAR with a Relay Pro or Relay NBS Pro stent-graft; diagnosis must be confirmed by contrast computed tomography angiography (CTA) or magnetic resonance imaging (MRI) within 3 months of the planned implant procedure. * Proximal and distal aortic necks suitable for stent-graft placement (i.e., diameter ranging between 18 and 42 mm) * Proximal and distal landing zones suitable for the stent-graft * Adequate vascular access for insertion of the delivery system, i.e., femoral or iliac arteries a minimum 6 mm in diameter to accommodate the 19 to 22-Fr outer-diameter delivery system and no excessive disease precluding delivery system entry/passage or iliac arteries that could be extended via an access conduit. * Written informed consent provided by the subject him/herself (not a representative) upon enrollment Exclusion Criteria: Patients who meet one or more of the following criteria are not eligible: * Aneurysm/lesion location not accessible to the delivery system and stent placement * Arterial access size insufficient for delivery system entrance or impossibility to perform a surgical access conduit * Treatment of lesion that would require a delivery system with usable length greater than 90 cm * Excessive arterial disease precluding delivery system entrance or passage * Systemic infection * Arterial tortuosity no…