Effect of Mindfulness Meditation on Physiological Response to Unpredictable Stimuli (NCT03206437) | Clinical Trial Compass
CompletedNot Applicable
Effect of Mindfulness Meditation on Physiological Response to Unpredictable Stimuli
United States45 participantsStarted 2017-06-20
Plain-language summary
This study will evaluate the effects of Mindfulness-Based Stress Reduction (MBSR) on physiological reactivity. This study will focus on individuals with anxiety who will participate in an 8-week MBSR class. The investigators will test participants' reactivity to both predictable and unpredictable stimuli before and after the class to understand the physiological changes that may occur after to the intervention. Secondary measures include psychometric instruments and a delay discounting task.
Who can participate
Age range18 Years – 65 Years
SexALL
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Inclusion criteria
✓. Men and women from 18-65 years of age.
✓. Have an anxiety disorder, including: social anxiety disorder (SAD), generalized anxiety disorder (GAD), panic disorder, posttraumatic stress disorder (PTSD), agoraphobia, or simple phobia.
✓. Must understand study procedure and willing to participate in 2 testing visits, and MBSR course as assigned.
✓. Participants must be able to give informed consent to the study procedures.
Exclusion criteria
✕. Subjects experiencing a current depressive episode or other axis I psychiatric disorders such as psychotic disorders, obsessive compulsive disorder, current eating disorders, bipolar disorder, and current substance use disorders.
✕. Lack of measurable eye blink/eye twitch response (3 times the baseline eye blink muscle activity as measured by electromyography) for at least 5 of 9 startles used during the habituation visit.
✕. A serious medical condition that may result in surgery or hospitalization.
✕. Subjects who will be non-compliant with the study procedures. This may include planned travel out of town.
✕. Women who are pregnant.
✕. Current evidence of median nerve entrapment or carpal tunnel syndrome.
✕. Subject who has resting blood pressure outside of a systolic blood pressure range of 90-140 mmHg, or a diastolic blood pressure outside a range of 50-90 mmHg on two consecutive measurements, taken up to 10 minutes apart.