Tissue-engineered Construct Based on Buccal Mucosa Cells and Matrix From Collagen and Polylactoglycolide Fibers

Inclusion Criteria: * Patient signed informed consent form * Diagnosed anterior urethral stricture longer than 2.0 cm and shorter than 4.0 cm * At least one prior internal optical urethrotomy and/or urethral bougienage Non-inclusion Criteria: * Acute infectious diseases * Patient with decompensated heart and renal failure * Patient with non-compensated diabetes mellitus * Patient with malignant tumor * Patient with polyvalent allergy * Mental disorders * Post traumatic urethral strictures * Subtotal and total urethral strictures * Sexually transmitted infections * Hypersensitivity to any components of tissue-engineered constructs * Any clinical state which does not ensure the safe implementation of study procedure (investigator's view) * Other associated urethral strictures * Laboratory markers of active urethritis Exclusion Criteria: * Patient's refusal from the further participation in trial * Confirmed syphilis, HIV, hepatitis B or C infections * Patient who cannot be regularly examined due to any circumstances