Reversible cerebral vasoconstriction syndrome (RCVS) is a clinico radiological entity characterized by severe headaches (associated or not with neurological complications) during one to 3 weeks, associated with a characteristic 'string and beads' appearance on cerebral arteries, which resolves spontaneously in 3 months. The pathway is unknown. At early stage of the disease (at the first medical consultation) cerebral arterial abnormalities which are necessary for diagnosis are identified in only 20% of patients (brain magnetic resonance imagery (MRI) ,CT scan angiography), appearing with a delay on 2th or 3rd week after the first severe headache.. Retinal artery network is considered to be a window on brain microvasculature by sharing the same embryologic origin and physiopathology. A retinal arteriolar examination at early stage of RCVS could provide non invasively early clue to confirm diagnosis by identifying anatomical change and /or functional abnormalities at the microvascular level, whereas large cerebral artery abnormalities are still normal.
Age range
18 Years – 80 Years
Sex
ALL
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The frequency of retinal morphological microvascular abnormalities
Timeframe: < 10 days
The frequency of retinal functional vascular abnormalities
Timeframe: < 10 days
The type of retinal morphological microvascular abnormalities
Timeframe: < 10 days
The type of retinal functional vascular abnormalities
Timeframe: < 10 days