Topical Antibiotic Prophylaxis for Eyelids (NCT03199911) | Clinical Trial Compass
CompletedPhase 4
Topical Antibiotic Prophylaxis for Eyelids
United States401 participantsStarted 2017-10-02
Plain-language summary
The investigators propose a prospective randomized control trial testing the hypothesis that routine topical antibiotic prophylaxis does not significantly reduce the rate of infection after eyelid surgery.
Who can participate
Age range18 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
Patients aged 18 and older who are undergoing various eyelid procedures in an office, ambulatory care center, or operating room including but not limited to:
* blepharoplasty (upper and lower lids);
* ectropion repair;
* entropion repair;
* external dacryocystorhinostomy;
* external levator resection;
* eyelid lesion removal and/or biopsy;
* eyelid reconstruction and defect repair including after Mohs surgery;
* fat pad excision (upper and lower lids);
* gold or platinum weight implantation;
* internal levator resection;
* lateral tarsal strip;
* orbital fracture repair requiring periorbital incisions;
* orbitotomy requiring periorbital incisions;
* tarsorrhaphy;
* wedge excision.
* Patients undergoing repeat procedures will also be included.
Exclusion Criteria:
* Patients aged younger than 18 years old who are undergoing the above eyelid procedures in an office, ambulatory care centers, operating rooms;
* patients undergoing chalazion removal;
* patients who have had previous wound infections at the site of the procedure;
* patients with oral or IV antibiotic use within 10 days prior to procedure;
* patients requiring IV antibiotics during the procedure;
* patients with grossly contaminated or inflamed wounds;
* patients with human or animal bites, patients with wounds resulting from trauma
* patients allergic to all study drug options.
What they're measuring
1
Number of Participants With Surgical Site Infections
Timeframe: First Post-Operative Visit (~7-14 days)