CompletedNot Applicable

Individualized Goal-directed Sufentanil Administration Versus Standard Therapy in Patients Undergoing Major Abdominal Surgery

France128 participantsStarted 2017-07-04

Plain-language summary

To determine whether a treatment strategy targeting an individualized sufentanil administration based on the Analgesia Nociception Index (ANI) could reduce the total dose of sufentanil during major abdominal surgery, as compared with standard practice.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age \>18 years * Elective major abdominal surgery * Estimated duration of surgery greater than 2 hours Exclusion Criteria: * Emergency abdominal surgery * Atrial fibrillation * Patient with pacemaker * Patient with heart transplant * Chronic beta-blockade * Intrathecal anesthesia * Conditions affecting SpO2 measurement (e.g., methemoglobinemia) * Morbid obesity (BMI\> 35 kg/m2) * Obstructive sleep apnea (OSA) * Person under legal guardianship or curatorship * No affiliation with the French health care system * Pregnant or breastfeeding women * Refusal to participate or inability to provide informed consent

What they're measuring

Total dose of sufentanil administered during major abdominal surgery

Timeframe: at day 0

Trial details

NCT IDNCT03166644

SponsorUniversity Hospital, Clermont-Ferrand

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2019-01-20

View on ClinicalTrials.gov More Major Abdominal Surgery trials