Treatment Off Gingival Recession Defects Using a Xenogenic Acellular Dermal Matrix Compared to Co… (NCT03162016) | Clinical Trial Compass
CompletedNot Applicable
Treatment Off Gingival Recession Defects Using a Xenogenic Acellular Dermal Matrix Compared to Connective Tissue Graft.
France12 participantsStarted 2017-06-23
Plain-language summary
Limitation of donor site and significant postoperative morbidity are often described in connective tissue graft harvesting. We want to show if mucoderm used in tunnel technique to recover miller class I and II recessions defects could be an alternative to connective tissue graft.
Who can participate
Age range45 Years
SexALL
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Inclusion Criteria:
* Patients \> 45 years, postmenopausal women (ie with amenorrhea for more than a year).
* Subject with bilateral Miller class I or II recessions defects
* non smoking patients
* patients having read and understood the information note on the study and signed the informed consent form.
* patients affiliated to the social security system.
Exclusion Criteria:
* Patient with absolute contra-indication for dental surgery: valvular heart disease at risk of infectious endocarditis, recent myocardal (≤ 12 months), organ transplants, recent placement of a coronary stent (≤ 12 months), transient ischemic attacks recurrent, cardiovascular instability, uncontrolled epilepsy, rheumatic fever.
* Patient with metabolic bone disease (Paget's disease, osteomalacia, osteogenesis imperfecta)
* Patient with an ASA score ≥ 3.
* Patient with absolute contra-indication to dental surgery
* Patient with severe hematologic disease
* Patient with I or type II diabetes
* Patients with previous or current acute illness or severe chronic cardiovascular, renal, hepatic, gastrointestinal, allergic, endocrine, neuro-psychiatric, considered by the investigator to be incompatible with the conduct of the study.
* Patients treated with retinoids, oral bisphosphonates, oral anticoagulants or anticonvulsants.
* Patient have or have had cancer of the upper aerodigestive tract treated by radiotherapy.
* Patient taking a steroidal or non-steroidal anti-inflammatory, anti-cancer or immunosuppres…