Nasal Ventilation Versus Voluntary Hypoventilation in the Rehabilitation of Hyperventilation Synd… (NCT03159429) | Clinical Trial Compass
TerminatedNot Applicable
Nasal Ventilation Versus Voluntary Hypoventilation in the Rehabilitation of Hyperventilation Syndrome
Stopped: Staff no longer available.
France19 participantsStarted 2017-10-05
Plain-language summary
The main objective of this study is to measure the effect (at 3 months) of dyspnea control rehabilitation with nasal ventilation versus standard rehabilitation, in dyspneic patients with hyperventilation syndrome.
Who can participate
Age range18 Years
SexALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* The patient must have given his / her free and informed consent and signed the consent
* The patient must be a member or beneficiary of a health insurance program
* The patient is available for 3 months of follow-up
* The patient has at least two of the following clinical symptoms consistent with hyperventilation sydrome: dyspnea, chest pain or pressure, visual blurring, dizziness, a sensation of abdominal swelling, tingling in the fingers, stiffness in the fingers or arms, tingling sensation around the mouth, cold or moist hands, tension or anxiety
* Resting hypocapnia defined by a PaCO2 \<38 mmHg and a normal O2 alveolo-arterial gradient D (A-a) O2
* Absence of significant obstructive or restrictive pathology according to respiratory function tests
* Absence of indirect signs of pulmonary arterial hypertension according to echocardiography
* Absence of alteration of gas exchange on maximum cardiopulmonary stress test (elevation of gradient D (A-a) O2 \> 35 mmHg at peak stress)
* At least 2 of the following criteria: (i) a Nijmegen questionnaire score \> 23, (ii) the recurrence of at least two common symptoms during the maximum cardiopulmonary stress test, (iii) delayed return of PETCO2 (partial pressure of end-tidal carbon dioxide) to its basal value (\> 5 minutes)
Exclusion Criteria:
* The subject is participating in another study
* The subject is in an exclusion period determined by a previous study
* The subject is under judicial protection, or i…