Preoperative Gabapentin for Chronic Pain After Thoracotomy (GABATHOMIE). (NCT03158376) | Clinical Trial Compass
CompletedPhase 3
Preoperative Gabapentin for Chronic Pain After Thoracotomy (GABATHOMIE).
France201 participantsStarted 2015-09
Plain-language summary
To assess the effects of prolonged preoperative gabapentin treatment (10 days) on chronic pain after thoracotomy.
Who can participate
Age range18 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* age \> 18 years
* elective lung resection via thoracotomy
Exclusion Criteria:
* extended pleurectomy and chest wall resection
* previous ipsilateral thoracotomy
* previous ipsilateral radiotherapy
* thoracotomy for pyothorax
* chest injury
* palliative surgery
* contraindicated placement of a thoracic epidural catheter
* allergy to medications on protocol
* pre-existing pain syndrome
* current treatment with morphine, gabapentin, pregabalin, anticonvulsivants or tricyclic antidepressants
* a history of past or current drug addiction
* severe hepatic, renal or cardiovascular disorders
* inability to understand the study protocol or to answer the questionnaires on pain and quality of life
* severe psychiatric disorders
* incompetent adults under some form of guardianship
* refusal of the protocol
* persons without social security coverage
* pregnant or lactating woman