Use of J3 Bioscience Lubricating Intravaginal Ring VR101 to Relieve the Symptoms of Vaginal Dryness

Inclusion Criteria: Potential participants must: * Completely understand and sign the informed consent form (ability to read and understand the consent form in the English language). * Be female 35 years of age or older. * Express willingness to comply with the study visit schedule (see Table 4 in study procedures section). * Over the course of the study: * Express willingness to abstain from the use of any vaginal moisturizers or lubricants or any other topically applied vaginal products not provided by study staff during VR101 or sham use, or during the Washout Period * Express willingness to abstain from the use of any HRT (hormone replacement therapy) or hormone-containing birth control products * Express willingness to abstain from use of any vaginal ring, diaphragm, cervical cap, or pessary products * In the previous 60 days, have self-reported vaginal dryness that interferes with daily activities, which may include sexual intercourse * Present with a VHI score of 22 or less, as scored by a trained clinician during the initial visit Exclusion Criteria: Potential participants self-reporting any of the following will be ineligible for study entry: * Current use of HRT (Hormone Replacement Therapy) or any hormone-containing birth control products. * Vulvar or vaginal procedures (biopsies, radiation) in the last 3 months * Active vulvar or vaginal infections/lesions or complaints, as well as undiagnosed abnormal genital bleeding * History of chronic pelvic pain,…