This is a pilot randomized clinical trial in which patients treated with 3X per weekly conventional hemodialysis will be treated to a dialysate sodium 135 mEq/L vs. 138 mEq/L and followed for safety and tolerability, effects on BP and volume.
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Frequency of Intradialytic Hypotension
Timeframe: Baseline period through study completion, an average of 6 months
Dialysis Dysequilibrium (Safety)
Timeframe: Baseline period through study completion, an average of 6 months
Frequency of ER visits and hospitalizations (safety)
Timeframe: Baseline through study completion
Frequency of patients treated to a dialysate Na 135 mEq/L at end of study (feasibility)
Timeframe: Last 2 weeks of Follow-up