High-Flow Heated and Humidified Oxygen Therapy and Gastric Distension (NCT03134937) | Clinical Trial Compass
CompletedNot Applicable
High-Flow Heated and Humidified Oxygen Therapy and Gastric Distension
Canada60 participantsStarted 2017-11-06
Plain-language summary
High Flow Heated and Humidified Nasal Oxygen therapy (HFHHNO) has been increasingly used in emergency medicine to assist patients with short term respiratory failure and to provide adequate oxygen to the body prior to intubation.
Gastric distension which is the bloating of the stomach due to air being pumped into it is a concern for anesthesiologists as it increases the risk of nausea and vomiting during surgery (aspiration).
The objective of this study is use an ultrasound machine to measure the volume of fluid in the stomach before and after HFNO is used in a standard clinical manner.
Who can participate
Age range18 Years – 70 Years
SexALL
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Inclusion criteria
✓. Healthy volunteers aged 18 to 70 years
✓. Male or female
✓. American Society of Anesthesia physical status classification I and II
✓. Height greater than 145 cm
✓. Ability to understand the study protocol and provide informed consent. Communication difficulties will not be an impediment to participate. In case of a language barrier, translation services will be sought as per usual institutional practice.
Exclusion criteria
✕. Subjects predisposed to have an increased residual gastric volume at baseline (e.g. diabetes or known gastric dysmotility)
✕. History of major upper gastrointestinal disease (including hiatus hernia or prior gastroduodenal surgery)
✕. Morbid obesity (Body Mass Index \> 40 Kg/m2)
✕. Chronic Obstructive Pulmonary Disease (Emphysema or Chronic Bronchitis)
What they're measuring
1
Change in Gastric Volume
Timeframe: Prior to, and immediately following session of HFHHNO oxygen therapy.