Outcome of 15 Versus 5 Fractions in Adjuvant Breast Radiotherapy in Women Over 65 Years

Inclusion Criteria: * breast conserving surgery or mastectomy for breast carcinoma * multidisciplinary decision of adjuvant irradiation * absence of distant metastases * informed consent obtained, signed and dated before specific protocol procedures Exclusion Criteria: * History of previous radiation treatment to the same region * Bilateral breast irradiation * Life expectancy of less than 2 years * Planned reconstructive breast surgery * Condition making toxicity evaluation difficult, e.g. skin disorders, pre-existing brachial plexus injury, … * Inability to respect constraints on skin, heart, lungs, esophagus, ribs, brachial plexus or any other organ at risk * Mental condition rendering the patient unable to understand the nature, scope and possible consequences of the study * Patient unlikely to comply with the protocol; i.e. uncooperative attitude, inability to return for follow-up visits or unlikely to complete the study