Ibuprofen Plus Acetaminophen Versus Oxycodone Alone After Hand Surgery (NCT03111186) | Clinical Trial Compass
CompletedPhase 2
Ibuprofen Plus Acetaminophen Versus Oxycodone Alone After Hand Surgery
United States40 participantsStarted 2017-04-24
Plain-language summary
This study is about pain control and medication following outpatient soft-tissue hand surgery. We hope to learn if ibuprofen and acetaminophen will achieve similar pain relief and satisfaction when compared with oxycodone alone.
Who can participate
Age range18 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* age greater than 18 years
* scheduled to undergo elective outpatient soft tissue hand surgery for one of the following procedures: Carpal tunnel release, Dupuytren contracture release, trigger digit release, ganglion cyst removal, de Quervain's release.
* primary language is English or Spanish
Exclusion Criteria:
* any pre-existing condition requiring preoperative opiate analgesia, eg chronic pain syndrome
* allergy to acetaminophen, ibuprofen, or oxycodone
* renal impairment or liver disease either documented based on history or when preoperative creatinine, BUN, or liver function tests are outside the normal range provided by the lab
* peptic ulcer disease or any history of gastrointestinal bleeding
* coagulopathy documented on history, review of systems, or based on preoperative lab testing where PT, PTT, or INR are outside the normal range provided by the lab
* pregnancy based on positive beta-HCG test which is performed on the day of the surgical procedure as is standard protocol
What they're measuring
1
change in VAS pain scale
Timeframe: baseline, daily - up to 1 week postoperative