Liposome Bupivacaine for ANKLE Blocks

Inclusion Criteria: * Male or female, at least 18 years and max 65 years of age at screening * Scheduled to undergo primary Scarf osteotomy for elective hallux valgus * American Society of Anesthesiologists (ASA) physical status 1, 2, or 3 * Female subject must be surgically sterile or have a monogamous partner who is surgically sterile; or be at least 2 years postmenopausal; or practicing abstinence; or using an insertable, injectable, transdermal, or combination oral contraceptive approved by the FDA for greater than 2 months prior to screening and commit to the use of an acceptable form of birth control for the duration of the study and for 30 days after completion of the study * Able to demonstrate sensory function by exhibiting sensitivity to cold, pinprick, and light touch * Able to understand the English or Dutch language, purpose and risks of the study, provide signed and dated informed consent and authorization to use protected health information (PHI) in accordance with national and local subject privacy regulations * Able to adhere to the study visit schedule, and complete all study assessments. Exclusion Criteria: * Currently pregnant, nursing, or planning to become pregnant during the study or within 1 month after study drug administration * Planned concurrent surgical procedure (e.g., bilateral hallux valgus repair) * Concurrent painful physical condition that may require analgesic treatment (such as an NSAID or opioid) in the postsurgical period for pain tha…