Comparison of Cadazolid Versus Vancomycin in Children With Clostridium Difficile-associated Diarrhea (CDAD)

Key Inclusion Criteria: * Signed informed consent by parents or legally authorized representatives (LAR) and assent by the child according to local requirements prior to initiation of any study-mandated procedure. * Male or female from birth to \< 18 years of age, diagnosed with Clostridium Difficile-associated diarrhea (CDAD). * Females of childbearing potential must have a negative pregnancy test at screening and must agree to use an adequate and reliable method of contraception. Key Exclusion Criteria: * Positive Rotavirus test for subjects \< 5 years. * Fulminant or life-threatening CDAD. * More than one previous episode of CDAD in the 3 month period prior to enrollment / randomization. * Antimicrobial treatment active against CDAD administered within 24 h prior to screening except for metronidazole treatment failures (MTF). * Subjects with body weight \< 3 kg. * Inflammatory bowel disease, chronic abdominal pain, or chronic diarrhea of any etiology. * Fecal microbiota transplant (FMT), immunoglobulin therapy, or any investigational drug to prevent or treat CDAD within 1 month period (or 5 half-lives in case of investigational drug, whichever is longer) prior to enrollment / randomization. * Monoclonal antibodies against C. difficile within 6 months prior to enrollment / randomization. * Previous vaccination against C. difficile. * Known mental disorders. * Any circumstances or conditions, which, in the opinion of the investigator, may affect the subject's full partici…