Impact of Enhanced External Counterpulsation on Vascular Hemodynamics and Status (NCT03102502) | Clinical Trial Compass
CompletedNot Applicable
Impact of Enhanced External Counterpulsation on Vascular Hemodynamics and Status
China110 participantsStarted 2017-03-10
Plain-language summary
The present study aimed to investigated the effect of Enhanced External Counterpulsation (EECP) on vascular hemodynamics and atherosclerosis, and the underlying shear stress related mechanisms
Who can participate
Age range20 Years – 80 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* More than 50% stenosis of left main trunk and 3 epicardial coronary arteries and their large branches showed by coronary angiography
* Or history of myocardial infarction
* Or history of prior revascularization
* Signed informed consent to participate in the study
Exclusion Criteria:
* Clinically significant valvular heart disease
* Aortic aneurysm
* Congenital heart disease
* Acute myocarditis
* Arrythmias significantly interfere with the triggering of the EECP device
* History of cerebral hemorrhage
* Hemorrhagic disease
* Lower limb infection, phlebitis
* Deep venous thrombosis
* Malignant disease
* INR \> 2.5
* Uncontrolled hypertension, defined as SBP \> 180mmHg or DBP \> 110mmHg
* Pregnancy
What they're measuring
1
Change in blood flow velocity
Timeframe: At baseline, during EECP and week 7 (post intervention)