Effect of Oral Supplementation With Probiotics

Inclusion Criteria: * body mass index (BMI) equal to or greater than 30 kg/m2 * age 45 to 70 years * stable body weight (\< 3 kg self-reported change during the previous three months) * written informed consent to participate in the study, * \> = 1 year after the last menstrual period; * abdominal obesity - waist circumference\> 80 cm; * body fat content measured by bio-impedance ≥ 33%; Exclusion Criteria: * secondary obesity or secondary hypertension * diabetes type I * gastrointestinal disease; * dyslipidaemia, type 2 diabetes, hypertension requiring the implementation of pharmacological treatment in the last 3 months prior to observation or follow-up; * a history of use of any dietary supplements within the one month prior to the study * taking antibiotics within 1 month before starting the study; * Clinically relevant acute or chronic inflammatory disease in the respiratory, gastrointestinal or genitourinary system or in the mouth, throat, paranasal sinuses and / or connective tissue disease, arthritis; * simultaneous participation in a study that affects weight change or use of diet / medication / nutritional behaviors affecting body weight changes; * consumption of pre- and probiotic-enriched products (for at least 3 weeks prior to the first screening visit) and products with high fiber content or large amounts of fermented foods (\> 400g / day); * hormone replacement therapy; * a history of infection in the month prior to the study * nicotine, drug or alcohol abuse …