The PREPPeD study proposes that predelivery placenta-derived maternal circulating biomarkers reflect placental health, capacity and ageing, and can help predict onset and complications of delivery both in complicated pregnancies as well as in clinically uncomplicated term/post-term pregnancies.
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Fetal acidaemia
Timeframe: Umbilical cord gas/lactate are sampled directly post partum within 45 min; data assessed throughout study period of 140 months
Newborn low Apgar score
Timeframe: Apgar score is assessed directly post partum within 10 minutes; data assessed throughout study period of 140 months
Newborn asphyxia
Timeframe: Directly post partum within 10 and 45 minutes respectively; data assessed throughout study period of 140 months
Rate of intrauterine fetal demise/intra-/postpartum fetal death
Timeframe: Diagnosis within 28 days postpartum; data assessed throughout study period of 140 months
Neonatal intubation/mechanical ventilation>6 hours
Timeframe: Within 28 days postpartum; data assessed throughout study period of 140 months
Meconium aspiration syndrome
Timeframe: Diagnosis within 28 days postpartum; data assessed throughout study period of 140 months
Neonatal hypoxic-ischemic encephalopathy
Timeframe: Diagnosis within 28 days postpartum; data assessed throughout study period of 140 months
Therapeutic hypothermia of the neonate
Timeframe: Within 3 days postpartum; data assessed throughout study period of 140 months
Rate of acute cesarean section (due to suspected fetal distress)
Timeframe: Data assessed throughout study period of 140 months