Transverse Coloplasty vs. Side-to-end Anastomosis Following Low Anterior Resection (LAR): CSAR Trial (NCT03074461) | Clinical Trial Compass
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Transverse Coloplasty vs. Side-to-end Anastomosis Following Low Anterior Resection (LAR): CSAR Trial
Germany80 participantsStarted 2017-04-05
Plain-language summary
CSAR Trial's aim is to determine whether the transverse coloplasty pouch or the side-to-end anastomosis as rectal reservoir reconstruction offers the best functional results.
Who can participate
Age range18 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Scheduled low anterior resection in patients with distal rectal carcinoma and planned anastomosis in mid/distal third of rectum
* Local curative approach
* Normal continence preoperatively
* Non-IBD-associated carcinoma
* Possible sphincter salvage
* Signed informed consent
Exclusion Criteria:
* Non-curative approaches
* Emergency surgery in cases of tumor perforation, abscess, sepsis
* Proximal rectal carcinoma (\> 12 cm from anocutaneous line)
* Lack of informed consent
* Age \<18 years
* Inclusion in other trials with interference of endpoints
* Life expectancy less than 24 months (as estimated by the treating physicians)
* Pregnancy
* Immunosuppression