Sinopsys Lacrimal Stent Study for Patients With Chronic Sinusitis or CRS

Inclusion Criteria: * The Investigator has determined that the potential study subject has moderate to severe chronic rhinosinusitis with ethmoid involvement: * Non-Contrast CT scan (coronal view) Total Zinreich Modified CT score of 10-41 * Inflammation/ involvement of the ethmoid sinus with left and/or right anterior ethmoid and/or posterior ethmoid Zinreich Modified CT scores of 1-4 * SNOT-22 total raw score ≥ 45 * Meets the American Academy of Otolaryngology - Head and Neck Surgery (AAO-HNS) criteria for chronic rhinosinusitis (CRS) (Rosenfeld, et al., 2007): 90 days or longer of two or more of the following signs and symptoms: Mucopurulent drainage (anterior, posterior, or both) Nasal obstruction (congestion) Facial pain-pressure-fullness, or Decreased sense of smell AND inflammation is documented by one or more of the following findings: Purulent (not clear) mucus or edema in the middle meatus or ethmoid region Polyps in nasal cavity or the middle meatus, and/or Radiographic imaging showing inflammation of the paranasal sinuses * Has failed medical therapy (Rudmik, et al., 2016) defined as the following: During the 90 days prior to enrollment, at a minimum: One course of broad spectrum or culture directed oral antibiotic of at least 2 weeks duration 60 days of topical intranasal steroid therapy and; 30 days of saline irrigation * Age ≥ 22 years * Non-Contrast CT scan (coronal view) confirms depth of olfactory fossa is Keros classification type 1 or 2 * The potential s…