Burst Biologics Spinal Fusion Registry

Inclusion Criteria: * Patient aged 18 years or older * Patient diagnosed with a degenerative spine disorder, has failed conservative treatment, and has decided to undergo surgery. * The surgeon has determined that a Burst Biologic product is or was clinically indicated. * Patient capable of understanding the content of the Informed Consent Form * Patient willing and able to participate in the registry protocol including follow-up visits and clinical evaluations. * Patient who has agreed to participate in the registry by providing consent according to the applicable local law and the declaration of Helsinki. Exclusion Criteria: The following are relative contraindications for the use of Burst Products, however the investigator surgeon is solely responsible for the determination of patient eligibility for surgery: * Severe vascular or neurological disease * Uncontrolled diabetes * Severe degenerative disease (other than degenerative disc disease) * Hypercalcemia, abnormal calcium metabolism * Existing acute or chronic infections, especially at the site of the operation * Inflammatory bone disease such as osteomyelitis * Malignant tumors * Patients who are or plan to become pregnant.