Identification/Characterization of Changes in Microscopic Colitis

Inclusion Criteria: * Ability to give informed consent * Ability and willingness to comply with all patient visits and study-related procedures * Ability to understand and complete all study-related materials and questionnaires * Patients ages 18 or older with suspected microscopic colitis * Patients that have been previously treated for microscopic colitis that are being seen for possible relapse will also be included Exclusion Criteria: * Inability to provide informed consent * Inability or unwillingness to comply with all patient visits and study-related procedures * Inability to understand and complete all study-related materials and questionnaires * Patients with a known diagnosis of Inflammatory Bowel Disease or colorectal cancer * Patients with a known bleeding disorder, acute disease, or those that are awaiting transplantation * Patients who have taken antibiotics in the last two weeks * Female subjects who are pregnant or nursing