Parecoxib Versus Celecoxib Versus Oxycodone in Pain Control for Transcatheter Chemoembolization Procedure

Inclusion Criteria: * Patients included in the study were classified with stage B or C according to the Barcelona Clinic Liver Cancer (BCLC) staging classification. * Patients were recommended to receive TACE therapy for HCC. Exclusion Criteria: * hypersensitive to celecoxib, parecoxib, and oxycodone * a history of serious allergic reactions to medicines * stomach ulcers or bleeding in the stomach or gut * allergic-type reactions such as bronchospasm, cold-like symptoms, polyps in the nose, swelling of the face or hives after taking aspirin or NSAIDs, including other COX-2 inhibitors * severe liver disease * inflammatory bowel disease * heart failure, ischaemic heart disease, peripheral artery disease, or cerebrovascular disease * women during the last three months of pregnancy or to breast-feeding women * after coronary surgery