A Lexico-semantic Program on Tactile Tablet for Patients With Alzheimer's Disease (NCT03047694) | Clinical Trial Compass
TerminatedNot Applicable
A Lexico-semantic Program on Tactile Tablet for Patients With Alzheimer's Disease
Stopped: Lack of inclusion
France1 participantsStarted 2019-07-15
Plain-language summary
Lexical semantic disorders are described in Alzheimer's disease, and their incidence in everyday life is important to the extent that these disorders affect expression and comprehension.
Providing a tactile tablet stimulation, independent and complementary to speech therapy, could help to maintain certain abilities and reinforce the feeling of autonomy of the patients.
Who can participate
Age range18 Years
SexALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
✓. Major Patient
✓. Patient with a diagnosis of Alzheimer's disease according to DSM-IV and NINCDS-ADRDA criteria.
✓. Patient at a moderate stage of the disease: Score at CDR (Clinical Dementia Rating Scale) between 0.5 inclusive and 2 inclusive and MMS score greater than or equal to 10 and lower strictly at 27
✓. Lexical-semantic disorder
✓. Treatment with pro-cognitive drugs at stable doses for at least 3 months,
✓. Speech therapy in progress (2 or 3 sessions per week)
✓. Patient with free and informed consent
✓. Affiliated to the Health care system
Exclusion criteria
✕. Other known neurological disease or general illness or major psychic problems that may interfere with cognitive functioning,
✕. Patient under guardianship or curatorship
✕. Confusion,
✕. Cerebral MRI (or scanner for contraindication to MRI), obtained in the context of routine care compatible with a pathological process other than that related to Alzheimer's disease. A discrete or moderate leukoaraiosis (stages 1 and 2 of Fazekas) will not be considered as a criterion of non-inclusion.
What they're measuring
1
variation of performance on naming subtest of the LEXIS
Timeframe: variation from baseline at 3 month
2
variation of performance on designation subtest of the LEXIS
Timeframe: variation from baseline at 3 month
3
variation of performance on semantic matching subtest of the LEXIS