Primary Objective: To evaluate the long-term outcomes including liver related morbidity, mortality and hepatocellular carcinoma (HCC) development as compared to those of historical control with interferon(IFN)-based treatment. Secondary Objective: 1. To access liver fibrosis progression/regression in CHC patients after sofosbuvir-based treatment. 2. To investigate the long-term outcomes of extrahepatic manifestations of the sofosbuvir-based treated cohort as compared to their pretreatment status.
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Number of participants with liver-related morbidity development during 5-year follow-up period after sofosbuvir-based treatment
Timeframe: 6 years
Number of participants with liver-related mortality development during 5-year follow-up period after sofosbuvir-based treatment
Timeframe: 6 years
Number of participants with hepatocellular carcinoma (HCC) development during 5-year follow-up period after sofosbuvir-based treatment
Timeframe: 6 years