This is a Phase 2a, multicenter, randomized, subject-blind, investigator-blind, study to investigate the pharmacokinetics (PK), pharmacodynamics (PD), and safety of bimekizumab in adult subjects with moderate to severe chronic plaque psoriasis
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Change From Baseline in Psoriasis Area and Severity Index (PASI) at Week 28
Timeframe: From Baseline to Week 28
Plasma Concentration of Bimekizumab at Baseline
Timeframe: at Baseline
Plasma Concentration of Bimekizumab at Week 2
Timeframe: at Week 2
Plasma Concentration of Bimekizumab at Week 4
Timeframe: at Week 4
Plasma Concentration of Bimekizumab at Week 8
Timeframe: at Week 8
Plasma Concentration of Bimekizumab at Week 12
Timeframe: at Week 12
Plasma Concentration of Bimekizumab at Week 16
Timeframe: at Week 16
Plasma Concentration of Bimekizumab at Week 20
Timeframe: at Week 20
Plasma Concentration of Bimekizumab at Week 24
Timeframe: at Week 24
Plasma Concentration of Bimekizumab at Week 28
Timeframe: at Week 28
Plasma Concentration of Bimekizumab at Week 36
Timeframe: at Week 36
Percentage of Participants Reporting Positive Anti-Drug-Antibodies (ADA) Titre Prior to Study Treatment With Bimekizumab at Baseline
Timeframe: at Baseline
Percentage of Participants Reporting an Overall Positive Anti-Drug-Antibodies (ADA) Titre Following Study Treatment With Bimekizumab
Timeframe: From Baseline to Safety Follow-Up Visit (Week 36)
Percentage of Participants Who Experienced at Least One Adverse Events (AEs)
Timeframe: From Screening to Safety Follow-Up Visit (Week 36)