Efficacy and Safety of Danoprevir/r + PR 12week Triple Therapy in Treatment Naive Non-Cirrhotic G1 CHC China III

Inclusion Criteria: * Willing and able to provide written informed consent * Chronic HCV infection (≥ 6 months) * Serum HCV RNA of ≥ 1 × 104 IU/mL are documented * Hepatitis C virus GT1 * Never received prior-treatment for HCV with interferon, RBV, or other direct-acting or host-targeting antivirals for HCV * Non-cirrhosis patients: Non-cirrhosis is defined (1)Fibroscan defined as: ˂ 14.6 kPa during screening period, or liver biopsy determined 1 year before recruiting (Metavir score ˂ 3);(2) during screening period 9.6\<Fibroscan indicator ≤12.9, liver biopsy need to confirm non-cirrhosis. * Others as specified in the detailed protocol Exclusion Criteria: * Patients with Fibroscan detection value \> 12.9 kPa, or histologic examination for liver cirrhosis patients * Presence or history of non-hepatitis C chronic liver disease (e.g. HH, AIH, Wilson's disease, α1 antitrypsin deficiency, drug- or toxin-induced liver disease) * History of liver cell cancer, or suspected hepatocellular carcinoma (HCC) patients before or during screening , or imaging studies found suspicious nodules, or AFP \> 50 ng/mL * Positive hepatitis A antibody，positive hepatitis B surface antigen，HIV antibody * Presence or history of nervous system diseases and/or mental illness, inability to control oneself or express oneself. * Patients with obvious cardiovascular dysfunction * Pregnant or nursing female, nor unwilling to take reliable contraception * Others as specified in the detailed protocol